Friday, September 28, 2012

Grow your own home with ancient and modern tech

Tiffany O'Callaghan, CultureLab editor

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(Image: DPA/Press Association Images)

An architect and designer with a PhD from the Massachusetts Institute of Technology, Mitchell Joachim is the founder of the non-profit green design group Terreform and a leader in the "urbaneering" movement, which invites communities to participate in urban design projects. His latest project is a collaboration between architects and biologists to construct a biosynthetic seat. New Scientist talked to him about experimenting with synthetic biology, his controversial "meat house" project and whether one day we'll be able to grow our own homes - and villages.

What is an example of a successful urbaneering project?
One of the earlier ones, the Brooklyn Navy Yard, was really successful. This was 300 acres [120 hectares] of urban space along the waterfront of New York that had been more or less inactive. We had? people involved in that neighbourhood and adjacent neighbourhoods, and a lot of architects and urban designers and planners discussing what we could do. Now we're turning the project into a space for clean tech and innovation.

How can we create the ideal city?
First and foremost you need to have the idea of what the ideal living space or urban environment might be - a picture of that utopic or semi-utopic space. I like to use the analogy of going to the gym. If you go to the gym and your goal is, "I want to look just like David Beckham," then that drives you to do certain things. You may never look like Beckham, but it is a goal. Cities need the same thing. They need a vision and a plan for their ideal physique.

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(Image: Mitchell Joachim, Lara Greden and Javier Arbona)

Your green project, Fab Tree Hab, is the idea for a house grown and constructed from living trees. What gave you the idea?
MIT was getting involved in solving the energy crisis. Buildings are certainly an enormous suck on the grid. In the architecture department we thought, well, even cutting down trees to bring them to a place to be built into something is a waste of energy. Let's just try growing them on site. We found technology that is 2500 years old, pleaching. We focused on that technology and combined it with our knowledge of 3D computation, building out complex geometries, to produce scaffolds that would nudge nature into a usable volume. We tried to be 100 per cent self-reliant - a home that was not efficient, and not zero, but really a positive contribution.

Do you think this is the future? Will we grow our own homes?
Well, yes, but I don't see it being universal. I think it will be one of many choices. This is the most extreme green version that I could possibly have thought of, but there will be many other solutions. I also understand the various problems with something like this. With any experimental house, there are various problems and this one requires understanding the field of botany and biology more than the typical architect, carpenter or developers would normally have to.

What is the synthetic biology seat you have been working on?
For the Genetic Generation Seat, or Gen2Seat, we've produced a new biopolymer. We took the base form of reishi mushrooms and combined it with cellulose made by acetobacter bacteria. Then my colleagues Oliver Medvedik and Ellen Jorgensen genetically expressed chitin [the chemical that makes insects' shells hard, among other things] inside the acetobacter to give it some level of waterproofing and hardness. All three of these elements combined to be a new biopolymer.

Another collaboration of yours that has got a lot of attention is the "meat house". What did that idea spring from?
The meat project was looking at tissue engineering and exploring some of the possibilities with regenerative medicine on what could happen with form - shapes and industrially designed objects - with those same techniques. There was an awful lot of rejection in the beginning. One research scientist that learned of the project was slightly upset, he said it was for cancer research, for people who need to replace a certain organ, and this use was demeaning.

But if we didn't put out the meat house, or in vitro meat habitat, as a kind of question on what else can we do with this particular subset of science, everything else would have been harder. The project attracted so many people, who thought, "Wow, we can hack tissue, what else can synthetic biology do?"

Sounds like it raised some questions
We still have very little understanding of how we can tweak form or shape at the genetic level. We certainly haven't unlocked those secrets. There have been some successes with small adjustments, but you can't look at a person's hand and say, "I know how that hand got to be that shape, I know how the geometry was determined and the volume was determined. I knew which genetic switch did that, what sequence caused it." I think this is where architects can absolutely get married to biologists. Once we know what creates shape, what the extents and limitations of form are, that becomes really exciting. It might not happen in my lifetime; maybe it is for the next generation.

What will we be able to do with this understanding?
Find the real extended phenotype of people. Birds have nests that seem to be inherent. I think there must be some kind of extended phenotype for humans. People probably have, inherently inside them the perfect psychological space that can be grown or developed at multiple levels. Maybe it's a womb or some kind of variant on a womb, something that's safe and performs or adapts to our needs. Right now I would say that is the big thesis question.

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Source: http://feeds.newscientist.com/c/749/f/10897/s/23ecc38c/l/0L0Snewscientist0N0Cblogs0Cculturelab0C20A120C0A90Cmitchell0Ejoachim0Einterview0Bhtml0DDCMP0FOTC0Erss0Gnsref0Fonline0Enews/story01.htm

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Monday, September 24, 2012

Small Business Hope for Romney and Ryan | US Daily Review

By US Daily Review.

Wave Accounting?(Wave), the creators of small business accounting and payroll software, today announced the results of its small business opinion poll on the 2012 U.S. Presidential Election. Wave polled the U.S.-based portion of the company?s more than 300,000 customers regarding their opinions on the candidates? potential impact on small business.

Key findings include:

  • On the question, ?Who is better for small businesses,? 53% of respondents chose?Romney/Ryan, 39% chose Obama/Biden.
  • Reducing government red tape is the number one issue for Republican voting respondents, with an overwhelming 90% citing this issue as ?crucial.?
  • Among voters intending to vote Democrat, the most important issue is improving health care options for small businesses (77% called it ?crucial.?)
  • Size matters: Support for?Romney/Ryan grows as company size grows. 47% of companies with 6-9 employees say they are definitely voting?Romney/Ryan, vs. 45% among companies with 2-5 employees, and 43% among one-person businesses.
  • Support for the GOP ticket is strongest in the South where 57% of businesses favor?Romney/Ryan.

?These insights represent the real opinions of real small businesses in America,? said?Kirk Simpson, CEO of Wave Accounting.

Recent ?small business? surveys have included opinions from companies with hundreds of employees and many millions in revenue. Because Wave specializes in online solutions for real small businesses with 9 employees or less, the company can access key insights from a unique and significant segment of the market.

?This group makes up 95% of businesses in the U.S., yet their voices are badly underrepresented in media and politics,? said Simpson. ?Their opinions and needs are interesting, in some cases unexpected, and deserve to be heard.?

The complete?Wave Small Business Opinions Report ? 2012 U.S. Presidential Election?is available at?www.waveaccounting.com/election2012.

?

Source: http://usdailyreview.com/small-business-hope-for-romney-and-ryan

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Thursday, September 13, 2012

Teen boy, Pa. Hershey school settle AIDS bias case

HERSHEY, Pa. (AP) ? A 14-year-old boy and his mother will receive $700,000 from the settlement of an AIDS discrimination lawsuit against a private boarding school that refused to enroll him because he's HIV-positive.

The settlement was announced Wednesday by the AIDS Law Project of Pennsylvania and the Milton Hershey School, which is financed by a trust that holds the controlling interest in The Hershey Co. candy manufacturer. The settlement is subject to court approval.

The school, for poor and socially disadvantaged students, also must pay $15,000 in civil penalties and provide HIV training for students and staff members.

The Philadelphia-based AIDS Law Project sued the school in federal court last year after it refused to enroll the boy, an honor roll student from the Philadelphia area, on the grounds that he would be a threat to other students' health and safety.

The school initially defended its decision, saying it was difficult but appropriate under the circumstances.

"In order to protect our children in this unique environment," the school said in December after the lawsuit was filed, "we cannot accommodate the needs of students with chronic communicable diseases that pose a direct threat to the health and safety of others."

The boy's attorney countered that he required no special accommodations and controlled his HIV with medication that wouldn't affect his school schedule.

"This young man is a motivated, intelligent kid who poses no health risk to other students but is being denied an educational opportunity because of ignorance and fear about HIV and AIDS," attorney Ronda Goldfein said then.

In August, the school reversed its policy and announced it would treat applicants with HIV the same as others.

The school, which has about 1,850 students in pre-kindergarten through 12th grade, also offered to admit the boy, identified in the lawsuit by the pseudonym Abraham Smith, but he and his mother decided he would seek other educational opportunities instead.

The school was founded in 1909 by chocolate maker Milton Hershey, whose company's products include Hershey's Kisses and Kit Kat. It's financed by the Milton Hershey School Trust and educates poor and socially disadvantaged students for free.

The Los Angeles-based AIDS Healthcare Foundation, which says it provides medical care to people with HIV and AIDS all over the world and contributed money to the boy's cause, welcomed news of the settlement.

"No doubt, advocacy aided this young man's quest for justice," foundation president Michael Weinstein said in a statement.

Around Easter, the foundation staged protests in San Francisco, New York City and Hershey, calling for a boycott of Hershey's candy and asking the public to send the company a message: "No Kisses for Hershey."

Source: http://news.yahoo.com/teen-boy-pa-hershey-school-settle-aids-bias-233820346.html

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Human stem cells restore hearing in gerbil study

This undated photo provided by Nature shows cells in the cochlea of deaf gerbils. The yellow ones are nerve cells derived from human embryonic cells. These cells improved the hearing of the gerbils, in an experiment that may someday help human patients. Results of the work, done in gerbils, were reported online Wednesday, Sept. 12, 2012 in the journal Nature by a team led by Dr. Marcelo Rivolta of the University of Sheffield in England. (AP Photo/Nature, University of Sheffield, Marcelo Rivolta)

This undated photo provided by Nature shows cells in the cochlea of deaf gerbils. The yellow ones are nerve cells derived from human embryonic cells. These cells improved the hearing of the gerbils, in an experiment that may someday help human patients. Results of the work, done in gerbils, were reported online Wednesday, Sept. 12, 2012 in the journal Nature by a team led by Dr. Marcelo Rivolta of the University of Sheffield in England. (AP Photo/Nature, University of Sheffield, Marcelo Rivolta)

(AP) ? For the first time, scientists have improved hearing in deaf animals by using human embryonic stem cells, an encouraging step for someday treating people with certain hearing disorders.

"It's a dynamite study (and) a significant leap forward," said one expert familiar with the work, Dr. Lawrence Lustig of the University of California, San Francisco.

The experiment involved an uncommon form of deafness, one that affects fewer than 1 percent to perhaps 15 percent of hearing-impaired people. And the treatment wouldn't necessarily apply to all cases of that disorder. Scientists hope the approach can be expanded to help with more common forms of deafness. But in any case, it will be years before human patients might benefit.

Results of the work, done in gerbils, were reported online Wednesday in the journal Nature by a team led by Dr. Marcelo Rivolta of the University of Sheffield in England.

To make the gerbils deaf in one ear, scientists killed nerve cells that transmit information from the ear to the brain. The experiment was aimed at replacing those cells.

Human embryonic stem cells can be manipulated to produce any type of cell. Using them is controversial because they are initially obtained by destroying embryos. Once recovered, stem cells can be grown and maintained in a lab and the experiment used cells from lab cultures.

The stem cells were used to make immature nerve cells. Those were then transplanted into the deaf ears of 18 gerbils.

Ten weeks later, the rodents' hearing ability had improved by an average of 46 percent, with recovery ranging from modest to almost complete, the researchers reported.

And how did they know the gerbils could hear in their deafened ears? They measured hearing ability by recording the response of the brain stem to sound.

The gerbils were kept on medication to avoid rejecting the human cells, much like people who get transplants of human organs, Rivolta said. But that might not be necessary if the procedure proceeds to people, he said. Scientists may be able to work with stem cells that closely match a patient, or even use a different technology to make the transplanted cells from a patient's own tissue, he said.

Rivolta's team also reported making immature versions of a second kind of inner-ear cell. Transplants of those cells might be able to treat far more cases of hearing loss. But the team has not yet tested these in animals, Rivolta said.

Yehoash Raphael of the University of Michigan, who didn't participate in the work, said it's possible the stem cell transplants worked by stimulating the gerbils' own few remaining nerve cells, rather than creating new ones. But either way, "this is a big step forward in use of stem cells for treating deafness," he said.

___

Online:

Nature: http://www.nature.com

___

Malcolm Ritter can be followed at http://twitter.com/malcolmritter

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/b2f0ca3a594644ee9e50a8ec4ce2d6de/Article_2012-09-12-US-SCI-Stem-Cells-Deafness/id-79c1f82ae98240d49d8e33485cde5f30

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Why Apple Made Three iPhone 5 Models and What That Means For You

Apple is finally making the iPhone compatible with LTE networks. But it's not all good news. Due to 4G fragmentation, Apple has had to make three different iPhone models. What does this mean for you?

Source: http://feedproxy.google.com/~r/GearFactor/~3/lKLP1UBnhMo/

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Friday, September 7, 2012

Audience Says Apple is 'Unlikely' to Use Its Technology in the New iPhone

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Audience has announced that it's unlikely that Apple will use its technology in the next generation iPhone tanking its stock by over 50% in after hours trading.

Here's the announcement:

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Audience sells processors and licenses its processor IP to Apple Inc. and certain of its subsidiaries (collectively, OEM) for inclusion in the OEM's mobile phones pursuant to a Master Development and Supply Agreement (MDSA). Pursuant to a statement of work under the MDSA, amended in March 2012, Audience developed and licensed a new generation of processor IP for use in the OEM's devices. However, the OEM is not obligated to use Audience's processor IP.

Audience now believes that it is unlikely that the OEM will enable Audience's processor IP in its next generation mobile phone. Audience is not aware of any intended changes by this OEM to its use of Audience's processors or processor IP in prior generations of the OEM's mobile phones.

Audience recognizes royalty revenue from the license of its processor IP one quarter in arrears of the sale of the device, when it has received a royalty report from its OEM. As a result, Audience does not expect any impact on its business outlook for the third fiscal quarter from the situation described above. The revenue and net income impact of the OEM's next generation mobile phone would first affect Audience's financial results one quarter after the OEM commences end customer sales of its mobile phones.
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